Hundreds of organic acid metabolites are found in the urine of all mammals, including humans. These metabolites can be used for both diagnostic and therapeutic measurements for detecting abnormal gastrointestinal overgrowth or dysbiosis, assessing mitochondrial energy production, detecting genetic diseases, assessing malnutrition and suboptimum nutrition, revealing toxic exposure, finding alterations of neurotransmitter metabolites in neurological and psychiatric disorders, and assessing metabolites that cause severe inflammation in a variety of chronic illnesses.
Organic Acids Testing Workshop – Expired
This recorded seminar series expired on 24th February 2018
The recording expiry had been extended from the 24th of January to the 24th of February.
While the recordings will no longer be available, the notes and resources are still able to be viewed online on an ongoing basis.
Resources Mentioned Throughout Webinars:
- How Genetics Affects the Detoxification of Drugs and Environmental Toxicants
- Mental Health – Understanding the Risks for Developing Mental Health Disorders
- Methylation – How Methylation Affects Mental Health, Cardiac Health, and Detoxification
- Non-Metal Toxic Chemicals and Their Effects on Health
- Overview of Genetic Testing
- Oxalate Metabolism – Risks and Treatments
- The APoE Gene – Important Risk Factor for Alzheimer’s
The OAT evaluates for various fungal toxins, including specific markers for Candida. Many people rely on stool testing for Candida diagnosis and miss the presence of Candida toxins through the Organic Acid Test. Candida can lead to neurochemical imbalances in the brain, as well as sensory problems and self-stimulatory behavior (often seen in autism).
The OAT evaluates for two specific toxins related to Clostridia bacteria – HPHPA and 4-cresol. Both of these toxins can inhibit a dopamine converting enzyme, leading to excess dopamine and toxic reactions in the brain and nervous system. Problems such as moodiness, irritability, aggression, self-injurious behavior, sleep difficulties, and more can be associated with Clostridia bacteria overgrowth.
The OAT includes glycolic and glyceric acids in the oxalate section, which can differentiate between genetic and nutritional components in disturbed oxalate metabolism. Oxalates are compounds found in many foods, and can be worsened by Candida overgrowth. High oxalates are associated with pain in the joints, muscles, and connective tissues. They can also trap heavy metals (such as mercury, lead, and arsenic) in the body and lead to mineral imbalances. Certain behavioral issues and self-injurious tendencies have been associated with high oxalates.
The OAT evaluates for imbalances in serotonin (an important brain and nervous system chemical for mood, fine and gross motor skills, and calmness), as well additional markers that can indicate toxic stress in the brain and nervous system, such as quinolinic acid. High quinolinic acid suggests toxic stress in the brain and is important to evaluate before prescribing certain supplements, particularly L-Tryptophan which is commonly used to help with sleep.
This presentation will highlight various patient cases from clinical practice that show the role of biomedical intervention for various patient scenarios such as dietary therapy, yeast and Clostridia treatment, and methylation support.
Phospholipase A2 (PLA2), an enzyme found in snake and bee venom, as well as in human tissue, has been found to be elevated in a variety of inflammation-related disorders.,It is considered a good marker for increased risk of developing or worsening inflammatory conditions. This presentation will review the new information available about PLA2, including an ongoing pilot study with MS patients, methods for PLA2 testing, and treatments that reduce PLA2 levels and inflammation.